The Pittsburgh Pirates and St Louis Cardinals are scheduled to meet in MLB at PNC Park on Saturday, starting at 6:35PM ET.
José Quintana (1-1, 2.19 ERA) will get the ball for the Pirates, while the Cardinals are going with Miles Mikolas (3-2, 1.68 ERA).
Dimers' top betting picks for Cardinals vs. Pirates, plus game predictions and best odds, are detailed in this article.
This St Louis vs. Pittsburgh betting analysis is presented by PointsBet, which has an awesome 5x $100 Risk-Free Bets promo for new users.
Using advanced computer power and data, Dimers.com has simulated Saturday's Cardinals-Pirates MLB matchup 10,000 times.
Dimers' revolutionary predictive analytics model, DimersBOT, currently gives the Cardinals a 57% chance of beating the Pirates .
More: Cardinals vs. Pirates Simulated 10K Times
The Pirates are +1.5 underdogs against the Cardinals, with -135 at BetMGM the best odds currently available.
For the favored Cardinals (-1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at +115.
Caesars Sportsbook currently has the best moneyline odds for the Pirates at +125, which means you can bet $100 to profit $125, earning a total payout of $225, if they win.
Meanwhile, FanDuel Sportsbook currently has the best moneyline odds for the Cardinals at -136, where you can risk $136 to win $100, for a total payout of $236, if they come out on top.
The Over/Under is set at 9 with PointsBet, which currently has the best odds for the Over at -105, while Caesars Sportsbook currently has the best odds for the Under at -110.
As always, check out all the sportsbooks available in your state for the best MLB odds and lines.
According to DimersBOT, the Pirates (+1.5) are a 56% chance of covering the run line, while the 9-run Over/Under is a 53% chance of going Under.
More: Today's Best Bets for All Major Sports
Dimers' best bets are based on detailed simulations and betting intelligence to serve you the best possible plays 24/7.
Use our dynamic widget below to see the latest Moneyline, Over/Under and Run Line probabilities and odds for St Louis vs. Pittsburgh, and click or tap on See Matchup for more.
Dimers has full coverage of Saturday's Cardinals-Pirates matchup, including pregame predictions, top betting picks, and live win probabilities.
Don't forget, DimersBOT updates often, so keep an eye on this page for the latest betting insights before Cardinals vs. Pirates on Saturday May 21, 2022.
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Saturday's action between the Pirates and Cardinals at PNC Park is scheduled to commence at 6:35PM ET.
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Now you've got the 411 on Cardinals vs. Pirates, take a look at the latest betting coverage for all upcoming MLB games in our MLB Bet Hub. There you can find probabilities and odds, as well as our best bets for every single MLB matchup.
Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!
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